SARS-CoV-2 post-survival total antibodies quantitatively
Whether you have been ill and had a confirmed SARS-CoV-2 infection in the past, or whether you only suspect that you you may have passed the infection asymptomatically - if you want to find out, whether your body has developed antibodies to the virus that can protect you from getting sick again or alleviate the symptoms of another infection, perform a test for antibodies to SARS-CoV-2 virus total quantitative.
What is the antibody test after a SARS-CoV-2 infection? total quantitative?
The serological test involves the quantitative determination of antibodies total antibodies directed against SARS-CoV-2 coronavirus.
This test can confirm a history of infection with the SARS-Cov2 coronavirus (even if it was asymptomatic) and the production of neutralizing antibodies by the body. The test detects antibodies against the RBD domain located on the S-spike protein bound by the protein receptor ACE on the surface of cells. These are neutralizing antibodies that protect against infection with most mutant viruses SARS-CoV2.
This type of test is used in the diagnosis of of a history of infection in individuals without clinical symptoms and as an epidemiological retrospective study to detect individuals who have been in contact with the virus and may have developed immune mechanisms immunity.
The test detects antibodies directed against the domain of the RBD located on the spike S protein, bound by the receptor ACE protein receptor on the cell surface. As a result of binding to the receptor, the virus enters the host cells, where it it can multiply and infect more neighboring cells.
The production of antibodies can reduce the risk of re-infection contracting the disease, and in the event of a subsequent infection, the course of the infection in most patients
It is very important that the test be performed no sooner than 7-10 days after contact with a person with a diagnosed infection of COVID-19 or with a person suspected of being infected. The formation of antibodies takes time and performing the test too early may give a a false-negative result.
This type of test should not be used to diagnose active SARS-CoV-2 infection.Positive serologic test results are not the basis for confirmation of COVID-19.They do not indicate directly to the current presence of the virus in the patient's body. To confirm the presence of the virus, including during the period of highest infectivity, a molecular RT-PCR test or an antigenic
Tests used to quantify antibodies quantitatively are characterized by high sensitivity and specificity. This means that result is not subject to error due to the presence of a different virus other than SARS-CoV-2, and even low concentrations of the antibodies.
Who should take the antibody test after having been sickened by the SARS-CoV-2 total quantitatively?
Determination of total antibodies, directed against the SARS-CoV-2 coronavirus is dedicated primarily to patients who have a history of COVID-19 disease or may have been exposed to the virus, such as through confirmed illness of a household household member or co-worker, increased risk of infection during work, taking public transportation, shopping and other life situations. This test can also be performed on the patient after vaccination to find out whether the body has developed protective antibodies, however, the test will not distinguish by what what mechanism the antibodies were produced: whether after immunization or after being ill.
COVID-19 disease in most cases runs its course without characteristic symptoms or in the complete absence of symptoms.
Covid-19 disease is not a disease of the same type
The measurement range for this test is 0.4 to 250 BAU/ml This means that results of antibody concentrations above 250 BAU/ml will be presented as >250 BAU/ml, with no specific titer.
When testing for antibodies after an outbreak of SARS-CoV-2 total quantitatively:
- You will find out if your body has produced immune antibodies immune responses.
- You will know the concentration of neutralizing antibodies.
- You can monitor the concentration of neutralizing antibodies
- You can monitor their levels over time.
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Please note!
- In the early post-infection period, in addition to IgG antibodies, IgM antibodies are also present IgM antibodies are also present. In a test that determines antibodies total in such a case, both classes of Immunogobulins. On the result, however, the value is shown total without distinguishing the class.
- Not all test subjects produce antibodies after COVID-19 intercourse.
- This is a very individual characteristic of the individual. Antibodies may be formed at different times, in different concentrations or may be absent.
- Do not compare the concentration of antibodies performed by different methods even if the result is reported in the same units of BAU/ml. If you want to assess the dynamics of changes in antibody concentration over time then the test should be performed with the same test and in the same same laboratory.
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